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KMID : 0358420070500010167
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Korean Journal of Obstetrics and Gynecology
2007 Volume.50 No. 1 p.167 ~ p.172
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The usefulness of ovarian volume using 3D VOCAL transvaginal ultrasound, antral follicle count and age as predictors of menopause in pre- and postmenopausal women
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Kim Yun-Sook
Jeon Seob
Kim Jong-Su
Choi Seung-Do
Sunwoo Jae-Gun
Shin Young-Woo
Bae Dong-Han
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Abstract
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Objective: To evaluate the sensitivity and specificity of ovarian volume using 3D VOCAL and 2D ultrasound, antral follicle count, and age as predictors of menopausal status in pre- and postmenopausal women.
Methods: The subjects of this study were premenopausal (n=38) and postmenopausal (n=23) healthy women aged between 35 and 57 years of age who were interviewed about social, demographic, and medical conditions. These women underwent transvaginal ultrasound using 3D VOCAL and 2D probe to determine ovarian volume. Chi-square test was applied to evaluate the correlation between ovarian volume, antral follicle count, age and menopausal status. Receiver operating Characteristic (ROC) curves were elaborated to evaluate the sensitivity, specificity and positive and negative predictive values.
Results: Premenopausal women presented larger ovaries than postmenopausal women (p<0.01). Premenopausal women had a higher number of antral follicles than postmenopausal women (p<0.01). ROC curves showed that antral follicle count and ovarian volume using 3D VOCAL transvaginal probe were more sensitive and specific markers of menopausal status than age or ovarian volume using 2D transvaginal probe.
Conclusion: Ovarian volume and antral follicle count differ according to age in pre- and postmenopausal women. The data suggest that antral follicle count and ovarian volume using 3D VOCAL transvaginal probe are quite useful in predicting menopausal status.
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KEYWORD
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3D VOCAL ultrasonography, Menopause, Ovarian volume, Antral follicle count
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